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When Is a Kidney Transplant Necessary for IgAN Patients?

By 
the PicnicHealth Team

Mar 30, 2023 • 5 min read

Understanding Kidney Transplants: A Treatment Option for Kidney Failure

Kidneys play a vital role in keeping our bodies healthy. They are bean-shaped organs located just below the rib cage, on either side of the spine. They have three main functions in the human body: removing waste, removing drugs, and balancing fluids by producing urine. In addition, they also contribute to regulating blood pressure, promoting healthy bones, and controlling the production of red blood cells. However, for those with near-end-stage renal disease, a permanent kidney failure condition, a kidney transplant may be necessary. If you are considering a kidney transplant as a treatment option for kidney failure, you may be wondering what it is and how it works.

A kidney transplant is a surgical procedure where a healthy kidney is placed into a patient whose kidneys no longer function properly. The healthy kidney comes from either a living or deceased donor. End-stage renal disease occurs when a patient’s kidneys lose the ability to filter fluid and waste from the body, leaving harmful levels of waste behind. In general, when kidney’s lose 90% of their ability to function, a patient is diagnosed with end-stage renal disease or renal failure. This may occur due to diabetes, chronic high blood pressure, or several other kidney-related conditions. Without regular dialysis or a kidney transplant, end-stage renal failure can be fatal.

If a living kidney donor is available, they can choose to donate one of their two healthy kidneys to a person with end-stage renal disease. Most people can live healthy, everyday lives with one healthy kidney, and the donated kidney will take over the functions of the failed kidney. It’s important to remember that a kidney transplant will not cure kidney disease, and patients will need to monitor their transplant success carefully with their doctor.

If you are considering a kidney transplant, it’s important to speak with your healthcare provider to determine if it’s a viable option for you. People of all ages suffering from end-stage renal disease may be eligible for a kidney transplant. It’s a complex process, but with the right medical care, it can significantly improve your quality of life.

Kidney Transplant Requirements

A kidney transplant is often the best treatment option for most patients with end-stage renal failure. One of the most urgent questions surrounding transplants is how to get a kidney transplant faster. First, it is essential to understand kidney transplant requirements for donors and recipients. A transplant is not an option for everyone. For example, patients with other life-threatening diseases, such as certain types of cancers, infections, or uncorrectable heart disease, are not eligible for a kidney transplant. Therefore, working with your healthcare team to determine if a transplant is an option is imperative. Another way to find out if you meet the criteria for a transplant is to contact a transplant center to schedule an evaluation.

Once it is established that a patient has chronic irreversible kidney disease that is not responsive to any other treatments or surgeries, patients can seek a transplant. One of the main requirements for a kidney transplant is that the donor’s blood type must be compatible with the recipient’s blood type. Other criteria include extensive health examinations to rule out any possible disqualifying conditions or diseases, and patients must be able to tolerate major surgery. In addition to medical tests, patients must also undergo a mental health evaluation to make sure they are ready for the kidney transplant process. This is because having a kidney transplant can be stressful and emotionally challenging. The mental health evaluation is meant to help identify any potential issues that may need to be addressed before and after the transplant to ensure the best possible outcome for the patient.

A doctor's referral opens the door to the waitlist process. After receiving a referral, the next step is contacting a transplant hospital. There are hundreds of transplant hospitals in the United States. For example, Mayo Clinic’s kidney transplant criteria and many other transplant ho5spital criteria are consistent in requirements such as diagnosis of irreversible kidney failure not responsive to other treatments, along with a referral from a doctor. Following acceptance into a kidney transplant program, further testing and evaluations take place to determine eligibility and the best options for finding a transplant donor.

Once a patient has been accepted into a transplant program, they will be added to the United Network for Organ Sharing (UNOS) waitlist for a deceased donor kidney, and may also seek a living donor. Extensive testing is required before being eligible for the UNOS transplant list. Seeking out a living donor may shorten the wait for a kidney. Matching and compatibility are important factors in the kidney transplant process. A number of tests are performed to determine whether a donor kidney is a suitable match, including blood type, crossmatch, and human leukocyte antigen (HLA) testing. There are more than one hundred different antigens that can be present in the human body, so doctors carefully evaluate the antigens present in the donor and the transplant recipient to ensure compatibility.

When considering a kidney transplant, it’s important to understand that there are differences between receiving a kidney from a living donor versus a deceased donor. A kidney from a living donor typically functions immediately, whereas a deceased donor kidney may require dialysis until it starts working properly. However, both types of transplants have high success rates. If you’re considering a transplant from a living donor, the National Kidney Foundation’s PEER program can provide support and education for those seeking a living donor and those who want to become a donor to someone in need.

Kidney Transplant Procedure

A kidney transplant is an extensive surgical procedure that replaces a failing kidney with a healthy, functioning kidney from a living or deceased donor. The surgery usually takes around three to four hours and is performed under general anesthesia. During the transplant surgery, the surgeon makes an incision on one side of the abdomen and places the donated kidney in a different location, such as the front lower abdomen and pelvis area. The new kidney is then surgically attached, while the patient’s non-functioning kidney is usually left in place unless it’s causing complications.

After the transplant surgery, the new kidney will begin functioning and producing urine, often immediately. However, in some cases, it may take several days for the transplanted kidney to start working properly. If this happens, patients may require temporary dialysis until the kidney begins to function. It’s also common for patients to experience soreness around the surgical incision site during healing.

Recovery following a kidney transplant may take up to two weeks, and patients are advised to avoid strenuous activities during this time. Back sleeping is recommended for four weeks after the surgery to protect the surgical site and the new organ. Patients should also avoid exercises that strain the abdominal area or belly muscles, including high-intensity exercises like spin classes or other workouts that cause excessive exertion. While recovery is expected within one to two weeks, it may take up to one year to resume normal activities.

Kidney Transplant Success Rates and Costs

Patients of all ages can succeed with kidney transplants, and kidneys from younger donors can be used for older transplant recipients. Generally, a kidney transplant lasts an average of ten to twelve years, but various factors such as low-grade inflammation, disease, or other conditions can attack the new organ as it did the previous one, causing the kidney to expire. It is important to follow post-operative care instructions and attend regular check-ups with healthcare providers to monitor kidney function and prevent complications.

The cost of a kidney transplant surgery is significant, averaging over four hundred thousand dollars. However, resources are available to help with the cost, including insurance and financial assistance programs. Organizations like the National Kidney Foundation provide information and resources to help transplant patients and their families with the financial aspects of the surgery.

In addition, watching kidney transplant videos can be helpful for patients to prepare for pre-and post-operative care. These videos can answer questions about what to expect during surgery and provide information on recovery time, diet, and visiting restrictions. Patients who receive a successful kidney transplant can experience an increased life expectancy and improved quality of life.

Post-Transplant Care

After a successful kidney transplant, it is important for patients to follow a strict regimen of medications and lifestyle changes to maintain the health of the transplanted kidney and prevent complications. This includes taking immunosuppressive medications to prevent rejection of the new organ, as well as antibiotics to prevent infections. Patients will need to attend frequent follow-up appointments with their healthcare team to monitor kidney function, adjust medications, and address any concerns.

In addition to medication management, several lifestyle changes can help promote kidney health and prevent complications. These include:

  • Eating a healthy, balanced diet that is low in sodium and high in fruits, vegetables, and lean proteins
  • Maintaining a healthy weight through regular exercise and physical activity
  • Avoiding smoking and limiting alcohol consumption
  • Monitoring blood pressure and blood sugar levels closely
  • Practicing good hygiene and avoiding exposure to infectious diseases

With proper care and maintenance, a transplanted kidney can continue to function for many years, allowing patients to enjoy an improved quality of life and reduced risk of complications. It is important for patients to work closely with their healthcare team and follow all recommended guidelines for post-transplant care.

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Create a List

List the names of all the doctors, hospitals, and other facilities your loved one visits regularly, along with those they have visited in the past. Try to go back as far as you can, striving for at least the last 5-10 years, but do your best. Even if you can’t remember them all, having a strong baseline can help you quickly identify gaps in records.

Ensure You Have the Appropriate Legal Status

It is important to make sure that you are fully empowered to make decisions on behalf of your loved one with Alzheimer’s. Your relationship status with the patient may not be enough to legally give you access to your loved one's medical information. It is a good idea to talk to an expert about securing special legal status, such as Power of Attorney (POA), a legal document that allows an individual to name someone as their decision maker should they no longer be able to make decisions on their own.

Gather and Organize the Medical Records in One Place

It’s important to have all of your loved one’s medical records together in one spot. This makes it much easier for you and your loved one’s physicians to accurately map the patient’s medical journey and more easily share information between doctors. Fortunately, tools exist to make record management and access simple. A free resource like PicnicHealth helps you collect and organize all of this information. PicnicHealth’s intuitive timeline allows you to pinpoint data across the medical history, eliminating your need for keeping heavy binders filled with paper records or keeping track of multiple software portal logins.

Review the Medical Records to be an Informed Advocate

The better you understand your loved one's medical history, the better you can advocate on their behalf. Access and understanding of this information will help you to ask informed questions with physicians. Through regular communication backed by the data in the medical records, you can help your loved one’s care team develop a more successful care plan.

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1. Build a support network.

When you’re juggling appointment times and insurance claims, putting a robust support system together might not strike you as the most urgent task. Investing the time to cultivate relationships with people can turn to in times of need will pay dividends. The next time you need a last-minute ride or just someone to listen, you won’t be on your own.

There are many condition-specific support groups and support groups for caregivers generally in person or online. In addition to the encouragement and empathy they provide, support groups can be a helpful source of tips, resources, and recommendations for navigating caregiving.

2. Stay organized.

The backbone of effective caregiving is organization. Keep medical information, appointment schedules, and medication lists in order. Use a planner or a digital service like PicnicHealth to stay on top of your responsibilities. This attention to detail can prevent future complications and reduce day-to-day stress.

3. Explore treatments and clinical trials.

We’ve seen incredible breakthroughs in treatment over the past couple of years, powered by patients and their caregivers participating in research. Stay in the loop about the latest in medical advancements and available resources that could benefit your loved one. Whether it’s a new therapy option or a community service that aids independence, being informed can make a world of difference in the quality of care you provide.

4. Make time for self-care.

It may seem self-centered to focus on self-care—but when you feel good, you can be a better caregiver. Whether it’s exercise, a mindfulness practice, a soak in the bath, or just time to rest when you need it, carve out those moments in the day when you can unwind, reset, and stay healthy mentally and physically. Think of it as building up your reserves of kindness, patience, and understanding—which can only benefit your loved one. No one can pour from an empty cup.

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LC-FAOD Odyssey: A Preliminary Analysis, presented at INFORM 2021

Data from real-world medical records:

(from 13 patients with LC-FAOD)

16 yrs old

Median age at enrollment

38% Female

15 providers / patient

7.5 years of data / patient

Data from patient-reported outcome (PRO) survey

(from 13 patients with LC-FAOD)

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Tip: Download or print the poster at the end of this article to review before your next appointment!
However, it's important to consult with a healthcare provider or registered dietitian to determine the appropriate amount of protein for your individual needs. In general, a diet with moderate protein intake (about 0.8 grams per kilogram of body weight per day) is recommended for people with kidney diseases.

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A tablet, phone, or laptop with a working camera, microphone, and stable internet connection.
A quiet, distraction-free area with enough space to walk a few steps if applicable.
A chair that you can use during any movements or tasks you’ll be asked to perform.
The tripod mailed to you via Amazon.

What to Expect

Before your video call:

Book Your Assessment
Visit your to-do list on your PicnicHealth Research Dashboard or click the scheduling link sent to your email. Note: Search for “New task for the ORBIT-CIDP Study" to find the video call scheduling link.
Receive Confirmation
Check your email for a confirmation with your scheduled video call time and instructions.

On the day of your video call:

Click on Video Link
Join your personal video call using the link we sent by email, or text message, or find it on your research dashboard.
Meet your nurse
A Registered Nurse (RN) will guide your virtual assessment, which will last about 30 minutes.
Complete the Physical Activity Assessment (INCAT)
The nurse will guide you through questions and, if needed, physical tasks to help researchers gain a deeper understanding of CIDP.
Complete the Movement Assessment (Optional)
If you participate, a nurse will guide you through three short recorded movement activities to complete as best you can:
Chair Task
While seated with your arms crossed over your chest and hands on oppositeshoulders, you’ll be asked to stand up, remain standing for 20 seconds, and then sit back down.
Arm Movement Task
While seated with your arms resting at your sides, you’ll be asked to raise both arms out to the sides until they meet above your head, then lower them back to your lap.
Finger Dexterity Task
While seated, raise your right hand with fingers extended. Touch your thumb to each fingertip in order, then reverse. Repeat with your left hand. This will then be repeated with your left hand.
Earn Compensation

Receive up to $55 for your participation:

  • $25 for completing the Physical Activity Assessment (INCAT).
  • $30 for the Optional Movement Assessment.
Recording: Your research assessment may be recorded to ensure accurate data collection. If you participate in the optional Movement Assessment, it will also be recorded. These recordings may capture your voice and responses, but identifiable information like your face, name, or background will be removed to protect your privacy.
Opt Into the Smart Insole Study Activity
Complete the opt-in survey to confirm your participation.
Receive Your Smart Insoles
Your smart insoles will be shipped to your home via FedEx and should arrive within 1 week.
Create Your Account

You’ll receive an email from Celestra Health with your account details. Follow those steps to set up your account.

  • If you don’t see an email from Celestra Health in your inbox, please check your spam or junk folder.
Download the App
After creating your account, you’ll be directed to a landing page with links to the App Store or Google Play. Use the link to download the correct version of the app for your device.
For illustrative purposes only, your insoles may look different
Log In
Open the app and log in using the email address and password you used when creating your account.
Enable Permissions
  • For iOS users: Enable Motion & Fitness and allow access to Apple Health.
  • For Android users: Enable Activity Recognition permissions.
Connect Your Insoles
Turn on Bluetooth, and follow the app's instructions to connect your smart insoles.
Enable Notifications
Enable push notifications to stay updated on reminders and activity progress.
For illustrative purposes only, your insoles may look different
Start Walking Sessions
When you’re ready to perform a walking session, tap ‘Start’ on the Ad Hoc Walking task card in the app.
Smart insoles are designed to fit comfortably into any pair of closed shoes
Need Help?
Should you need to contact Celestra Health support for any reason, you can submit a ticket through the Help section of the app by tapping the Submit A Ticket card and filling out the form. A Celestra Health representative will typically respond within one business day.
A fully charged device (smartphone, tablet, or laptop) with a working camera, microphone, and stable internet connection.
A quiet, well-lit space that is free from distractions.
Good lighting so your face is clearly visible; having a small flashlight or your phone’s flashlight nearby can help with skin, scalp, or joint checks.
Flexible device positioning so you can easily adjust or prop up your device hands-free if the research staff asks to view specific areas (such as your face, hands, or scalp).
Space to move in case you are briefly asked to stand or walk a few steps.
Your medication information, including your current steroid(s) and BENLYSTA® (belimumab) — either the medication bottles or a list with doses and schedule.
Time to focus without interruptions so the visit can be completed comfortably.
Before Your Video Call:
Schedule your visit
Use the scheduling link on your PicnicHealth Research Dashboard or the link sent to your email.
Tip: Search your inbox for “New task for the BEACON-SLE Study - schedule your remote visit” to find the scheduling email.
Check your confirmation
You’ll receive an email with your appointment time and instructions for joining the video call.
On the Day of Your Video Call:
Join the call
Click the Zoom link sent to you by email or text message, or use the link available on your research dashboard.
Meet with the research staff member
  • They will ask you structured questions about your health and any lupus symptoms you’ve experienced over the past 30 days.
  • If needed, they may guide you through a few simple visual checks (such as looking at your skin, hair, joints, or mouth). You can always tell them if you’re not comfortable with anything.
Receive Compensation
You’ll receive up to $60 for completing your visit.
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